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dc.contributor.advisorSoejarto, D. Doelen_US
dc.contributor.authorElkington, Bethany G.en_US
dc.date.accessioned2013-06-28T18:06:01Z
dc.date.available2013-06-28T18:06:01Z
dc.date.available2015-06-29T09:30:14Z
dc.date.created2013-05en_US
dc.date.issued2013-06-28
dc.date.submitted2013-05en_US
dc.identifier.urihttp://hdl.handle.net/10027/10030
dc.description.abstractIn the Lao PDR (Laos), centuries-old medical palm leaf manuscripts provide an invaluable record of traditional treatments through history. Today, traditional herbal remedies are still frequently used throughout the country. In effort to preserve the indigenous knowledge held by healers and the information contained in the sacred manuscripts, an attempt was made to translate some of the traditional healing practices into biomedical terms. To accomplish this, medical manuscripts were investigated for symptoms of tuberculosis, a problem that has been afflicting Southeast Asia for thousands of years. The corresponding treatments in the manuscripts were then translated into the modern Lao and English languages. Simultaneously, ethnobotanical interviews were conducted with contemporary healers throughout the country to see which plants they are currently prescribing for the same symptoms. Plant samples of the parts used traditionally were collected and documented with voucher herbarium specimens. In addition, two commercial multi-component products were analyzed. The samples were screened through in vitro biological assays against virulent Mycobacterium tuberculosis H37Rv (Mtb). The results demonstrated that some of the plants used in traditional remedies have in vitro activity against Mtb, and anti-Mtb compounds were isolated, providing some scientific support of the traditional claims. In addition, this research brings attention to the rich diversity of medicinal plants in Laos and will hopefully provide incentive to preserve the undeveloped forested areas that remain, which still hold a wealth of medical information for future discoveries.en_US
dc.language.isoenen_US
dc.rightsCopyright 2013 Bethany G. Elkingtonen_US
dc.subjectmedical ethnobotanyen_US
dc.subjecttraditional medicineen_US
dc.subjectethnopharmacologyen_US
dc.subjectpalm leaf manuscriptsen_US
dc.subjectTham scripten_US
dc.titleTraditional Herbal Treatments for Tuberculosis in Laos: Ethnobotany and Pharmacognosy Studiesen_US
thesis.degree.departmentMedicinal Chemistry and Pharmacognosyen_US
thesis.degree.disciplinePharmacognosyen_US
thesis.degree.grantorUniversity of Illinois at Chicagoen_US
thesis.degree.levelDoctoralen_US
thesis.degree.namePhD, Doctor of Philosophyen_US
dc.type.genrethesisen_US
dc.contributor.committeeMemberFranzblau, Scott G.en_US
dc.contributor.committeeMemberGyllenhaal, Charlotteen_US
dc.contributor.committeeMemberPauli, Guido F.en_US
dc.contributor.committeeMemberPatil, Crystalen_US
dc.contributor.committeeMemberZhang, Hongjieen_US
dc.contributor.committeeMemberHartmann, John F.en_US
dc.type.materialtexten_US


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