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dc.contributor.authorLi, Jingwei
dc.contributor.authorLee, Daesung
dc.date.accessioned2013-12-03T21:47:24Z
dc.date.available2013-12-03T21:47:24Z
dc.date.issued2012-11
dc.identifier.bibliographicCitationLi JW, Lee D. Diastereoselective ring-rearrangement metathesis to set the stereochemistry of all-carbon quaternary centres. Chemical Science. Nov 2012;3(11):3296-3301. DOI: 10.1039/c2sc20812aen_US
dc.identifier.issn2041-6520
dc.identifier.urihttp://hdl.handle.net/10027/10758
dc.descriptionPost print version of article may differ from published version. The definitive version is available through Royal Society of Chemistry at DOI:10.1039/c2sc20812aen_US
dc.description.abstractA highly diastereoselective ring-rearrangement metathesis of cyclopentene derivatives containing all-carbon quaternary centres is reported. This tandem metathesis process provides cyclohexenes derivatives with two contiguous stereogenic centres, one of which is an all-carbon quaternary stereogenic centre, in high yields and excellent diastereoselecitivity. The efficacy of this methodology is showcased in the total synthesis of spiropiperidine alkaloid nitramine. In the meantime, it has been found that metathesis of the corresponding acyclic triene derivatives affords the same products with the same level of efficiency and diastereoselectivity.en_US
dc.language.isoen_USen_US
dc.publisherRoyal Society of Chemistryen_US
dc.titleDiastereoselective Ring-Rearrangement Metathesis to Set the Stereochemistry of All-Carbon Quaternary Centresen_US
dc.typeArticleen_US


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