Now showing items 1-3 of 3
Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model
(Public Library of Science, 2013-03)
The current paradigm for studying hepatitis C virus (HCV) dynamics in patients utilizes a standard viral dynamic model that keeps track of uninfected (target) cells, infected cells, and virus. The model does not account ...
Meta-Analysis of Hepatitis C Virus Vaccine Efficacy in Chimpanzees Indicates an Importance for Structural Proteins
Studies in patients and chimpanzees that spontaneously cleared hepatitis C virus (HCV) infections demonstrated that natural immunity to the virus is induced during primary infections and that this immunity can be cross ...
Pharmacodynamics of PEG-IFN alpha-2a and HCV response as a function of IL28B polymorphism in HIV/HCV co-infected patients
(Lippincott, Williams & Wilkins, 2011-02)
We examined the association between IL28B single‐nucleotide‐polymorphism rs12979860, hepatitis C virus (HCV) kinetic and pegylated‐interferon‐alpha‐2a pharmacodynamic parameters in HIV/HCV‐co‐infected patients from South ...