Now showing items 1-2 of 2

    • Increased Adiposity, Dysregulated Glucose Metabolism and Systemic Inflammation in Galectin-3 KO Mice 

      Pang, Jingbo; Rhodes, Davina H.; Pini, Maria; Akasheh, Rand T.; Castellanos, Karla J.; Cabay, Robert J.; Cooper, Dianne; Perretti, Mauro; Fantuzzi, Giamila (Public Library of Science, 2013-02)
      Obesity and type 2 diabetes are associated with increased production of Galectin-3 (Gal-3), a protein that modulates inflammation and clearance of glucose adducts. We used Lean and Diet-induced Obese (DIO) WT and Gal-3 KO ...
    • Rosiglitazone Improves Survival and Hastens Recovery from Pancreatic Inflammation in Obese Mice 

      Pini, Maria; Rhodes, Davina H.; Castellanos, Karla J.; Cabay, Robert J.; Grady, Eileen F.; Fantuzzi, Giamila (Public Library of Science, 2012-07)
      Obesity increases severity of acute pancreatitis (AP) by unclear mechanisms. We investigated the effect of the PPAR-gamma agonist rosiglitazone (RGZ, 0.01% in the diet) on severity of AP induced by administration of IL-12+ ...