Now showing items 1-4 of 4

    • Hematological and acute-phase responses to diet-induced obesity in IL-6 KO mice 

      Pini, Maria; Rhodes, Davina H.; Fantuzzi, Giamila (Elsevier, 2011-12)
      Obesity is associated with chronic inflammation and elevated levels of IL-6. The role of IL-6 in induction of acute-phase proteins and modulation of haematological responses has been demonstrated in models of inflammation ...
    • Increased Adiposity in Annexin A1-Deficient Mice 

      Akasheh, Rand T.; Pini, Maria; Pang, Jingbo; Fantuzzi, Giamila (PLoS One, 2013-12)
      Production of Annexin A1 (ANXA1), a protein that mediates the anti-inflammatory action of glucocorticoids, is altered in obesity, but its role in modulation of adiposity has not yet been investigated. The objective of this ...
    • Increased Adiposity, Dysregulated Glucose Metabolism and Systemic Inflammation in Galectin-3 KO Mice 

      Pang, Jingbo; Rhodes, Davina H.; Pini, Maria; Akasheh, Rand T.; Castellanos, Karla J.; Cabay, Robert J.; Cooper, Dianne; Perretti, Mauro; Fantuzzi, Giamila (Public Library of Science, 2013-02)
      Obesity and type 2 diabetes are associated with increased production of Galectin-3 (Gal-3), a protein that modulates inflammation and clearance of glucose adducts. We used Lean and Diet-induced Obese (DIO) WT and Gal-3 KO ...
    • Rosiglitazone Improves Survival and Hastens Recovery from Pancreatic Inflammation in Obese Mice 

      Pini, Maria; Rhodes, Davina H.; Castellanos, Karla J.; Cabay, Robert J.; Grady, Eileen F.; Fantuzzi, Giamila (Public Library of Science, 2012-07)
      Obesity increases severity of acute pancreatitis (AP) by unclear mechanisms. We investigated the effect of the PPAR-gamma agonist rosiglitazone (RGZ, 0.01% in the diet) on severity of AP induced by administration of IL-12+ ...