Now showing items 1-1 of 1

    • CIB1 is an endogenous inhibitor of agonist-induced integrin aIIbb3 [alpha II b beta 3]activation 

      Yuan, Weiping; Leisner, Tina M; McFadden, Andrew W; Wang, Zhengyan; Larson, Mark K; Clark, Shantres; Boudignon-Proudhon, Christel; Lam, Stephen CT; Parise, Leslie V (Rockefeller University Press, 2006-01-17)
      In response to agonist stimulation, the alpha IIb beta 3 integrin on platelets is converted to an active conformation that binds fibrinogen and mediates platelet aggregation. This process contributes to both normal hemostasis ...