Now showing items 1-3 of 3
Regulation of ER-phagy by a Ypt/Rab GTPase module
(American Society for Cell Biology, 2013-10)
Accumulation of misfolded proteins on intracellular membranes has been implicated in neurodegenerative diseases. One cellular pathway that clears such aggregates is endoplasmic reticulum autophagy (ER-phagy), a selective ...
Regulation of Selective Autophagy Onset by a Ypt/Rab GTPase Module
(National Academy of Sciences, 2012-05)
The key regulators of intracellular trafficking, Ypt/Rab GTPases, are stimulated by specific upstream activators and, when activated, recruit specific downstream effectors to mediate membrane transport events. The yeast ...
Bringing host-cell takeover by pathogenic bacteria to center stage: Editorial
(Landes Bioscience, 2011)
Intra-cellular pathogenic bacteria contrive processes in their host cell to create a niche for their own reproduction. One way that has emerged by which bacteria do that is delivery of secreted virulence factors, SVFs, ...