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The crystal structure of yeast mitochondrial ThrRS in complex with the canonical threonine tRNA
(Oxford University Press, 2015)
In mitochondria of Saccharomyces cerevisiae, a single aminoacyl- TRNA synthetase (aaRS), MST1, aminoacylates two isoacceptor tRNAs, tRNA1 Thr and tRNA2 Thr, that harbor anticodon loops of different size and sequence. As a ...
Identification of a Unique Inhibitor-Binding Site on Choline Kinase α
(American Chemical Society, 2018-02-01)
Choline kinase α (ChoKα) is an enzyme that is upregulated in many types of cancer and has been shown to be tumorigenic. As such, it makes a promising target for inhibiting tumor growth. Though there have been several ...