Now showing items 1-3 of 3
Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway
(Rockefeller University Press, 2006-10-23)
Prevailing models place spectrin downstream of ankyrin in a pathway of assembly and function in polarized cells. We used a transgene rescue strategy in Drosophila melanogaster to test contributions of four specific functional ...
The Drosophila Anion Exchanger (DAE) lacks a detectable interaction with the spectrin cytoskeleton
(BioMed Central, 2010-06-23)
Background: Current models suggest that the spectrin cytoskeleton stabilizes interacting ion transport proteins at the plasma membrane. The human erythrocyte anion exchanger (AE1) was the first membrane transport protein ...
Transgene rescue identifies an essential function for Drosophila beta spectrin in the nervous system and a selective requirement for ankyrin-2-binding activity
(American Society for Cell Biology, 2010-08-15)
The protein spectrin is ubiquitous in animal cells and is believed to play important roles in cell shape and membrane stability, cell polarity, and endomembrane traffic. Experiments here were undertaken to identify sites ...