The ups and downs of drug discovery: the early history of Fidaxomicin
McAlphine, James, B.
PublisherNature Publishing Group
MetadataShow full item record
The path, from antibiotic compound discovery to the market, is marked by many potholes and its negotiation is often dependent on luck and persistence. Perhaps the prime example of this is the case of Tiacumicin B to Fidaxomicin®, where both parameters were critical and the path was particularly circuitous.