Browsing Publications -Medicine by Title
Now showing items 1-14 of 14
-
Breakthroughs in genomics data integration for predicting clinical outcome
(Elsevier, 2012-12) -
A High Degree of LINE-1 Hypomethylation Is a Unique Feature of Early-Onset Colorectal Cancer
(Public Library of Science, 2012-09)Objective: Early-onset colorectal cancer (CRC) represents a clinically distinct form of CRC that is often associated with a poor prognosis. Methylation levels of genomic repeats such as LINE-1 elements have been recognized ... -
Identification of ChIP-seq mapped targets of HP1β due to bombesin/GRP receptor activation
(BioMed Central, 2011-08)Epithelial cells lining the adult colon do not normally express gastrin-releasing peptide (GRP) or its receptor (GRPR). In contrast, GRP/GRPR can be aberrantly expressed in human colorectal cancer (CRC) including Caco- 2 ... -
Inclusion, Analysis, and Reporting of Sex and Race/Ethnicity in Clinical Trials: Have We Made Progress?
(Mary Ann Liebert, 2011-03-15)Background: The National Institutes of Health (NIH) Revitalization Act of 1993 requires that NIH-funded clinical trials include women and minorities as participants; other federal agencies have adopted similar guidelines. ... -
Integrating women's human rights into global health research: an action framework
(Mary Ann Liebert, 2010-11)This article uses Scale of Change theory as a framework to guide global health researchers to synergistically target women's health outcomes in the context of improving their right to freedom, equity, and equality of ... -
Introduction to the Special Section on Global Women's Reproductive Health
(Mary Ann Liebert, 2010-11-04)We welcome you to the Journal of Women’s Health 2010 special section on global women’s reproductive health. Access to a full range of reproductive healthcare is fundamental to a woman’s ability to exercise her right to ... -
MPD-RC 101 prospective study of reduced-intensity allogeneic hematopoietic stem cell transplantation in patients with myelofibrosis
(American Society of Hematology, 2014)From 2007 to 2011, 66 patients with primary myelofibrosis or myelofibrosis (MF) preceded by essential thrombocythemia or polycythemia vera were enrolled into a prospective phase 2 clinical trial of reduced-intensity ... -
Navigating the Challenges of Global Reproductive Health Research
(Mary Ann Liebert, 2010-11)Reproductive health research in low-resource settings poses unique and complex challenges that must be addressed to ensure that global research is conducted with strict adherence to ethical principles, offers direct benefit ... -
Nitric oxide donor [Ru(terpy)(bdq)NO]3+ induces uncoupling and phosphorylation of endothelial nitric oxide synthase promoting ROS and peroxynitrite production
(Elsevier, 2017-11-01)TERPY is a nitric oxide (NO) donor that promotes relaxation of the mesenteric artery and aorta in rats. We sought to investigate whether it acts as both an NO donor and endothelial NO synthase (eNOS) activator, as shown ... -
Quantitative FRET Imaging to Visualize the Invasiveness of Live Breast Cancer Cells
(Public Library of Science, 2013-03)Matrix metalloproteinases (MMPs) remodel tumor microenvironment and promote cancer metastasis. Among the MMP family proteases, the proteolytic activity of the pro-tumorigenic and pro-metastatic membrane-type 1 ... -
Relating through differences: disability, affective relationality, and the U.S. public healthcare assemblage
(PALGRAVE MACMILLAN LTD, 2017-04)Using affect theory and disability theory, this article theorizes relationality as it emerges between disabled people who require daily assistance and their paid care providers. In response to the question of how people ... -
Selective Modulation of Endoplasmic Reticulum Stress Markers in Prostate Cancer Cells by a Standardized Mangosteen Fruit Extract
(PLOS ONE, 2013-12-25)The increased proliferation of cancer cells is directly dependent on the increased activity of the endoplasmic reticulum (ER) machinery which is responsible for protein folding, assembly, and transport. In fact, it is so ... -
Steroid receptor coactivator 1 deficiency increases MMTV-neu mediated tumor latency and differentiation specific gene expression, decreases metastasis, and inhibits response to PPAR ligands
(BioMed Central, 2010-11-16)Background: The peroxisome proliferator activated receptor (PPAR) subgroup of the nuclear hormone receptor superfamily is activated by a variety of natural and synthetic ligands. PPARs can heterodimerize with retinoid X ... -
Transcriptional Regulation of the Ufm1 Conjugation System in Response to Disturbance of the Endoplasmic Reticulum Homeostasis and Inhibition of Vesicle Trafficking
(Public Library of Science, 2012-11)Homeostasis of the endoplasmic reticulum (ER) is essential for normal cellular functions. Disturbance of this homeostasis causes ER stress and activates the Unfolded Protein Response (UPR). The Ufm1 conjugation system is ...