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    • APOE4-specific Changes in A beta Accumulation in a New Transgenic Mouse Model of Alzheimer Disease 

      Youmans, Katherine L.; Tai, Leon M.; Nwabuisi-Heath, Evelyn; Jungbauer, Lisa; Kanekiyo, Takahisa; Gan, Ming; Kim, Jungsu; Eimer, William A.; Estus, Steve; Rebeck, G. William; Weeber, Edwin J; Bu, Guojun; Yu, Chunjiang; LaDu, Mary Jo (American Society for Biochemistry and Molecular Biology, 2012-12)
      APOE4 is the greatest risk factor for Alzheimer disease (AD) and synergistic effects with amyloid-beta peptide (A beta) suggest interactions among apoE isoforms and different forms of A beta accumulation. However, it remains ...