Browsing Publications - Anatomy and Cell Biology by Subject "lysosome"
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Differential Regulation of Amyloid-β Endocytic Trafficking and Lysosomal Degradation by Apolipoprotein E Isoforms (American Society for Biochemistry and Molecular Biology, 2012-12)Aggregation of amyloid-beta (A beta) peptides leads to synaptic disruption and neurodegeneration in Alzheimer disease (AD). A major A beta clearance pathway in the brain is cellular uptake and degradation. However, how A ...