Now showing items 1-1 of 1

    • Optimization of the Capsid of Recombinant Adeno-Associated Virus 2 (AAV2) Vectors: The Final Threshold? 

      Aslanidi, George V.; Rivers, Angela E.; Ortiz, Luis; Song, Liujiang; Ling, Chen; Govindasamy, Lakshmanan; Van Vliet, Kim; Tan, Mengqun; Agbandje-McKenna, Mavis; Srivastava, Arun (Public Library of Science, 2013-03)
      The ubiquitin-proteasome pathway plays a critical role in the intracellular trafficking of AAV2 vectors, and phosphorylation of certain surface-exposed amino acid residues on the capsid provides the primary signal for ...