Now showing items 1-4 of 4
MicroRNAs Implicated in Dysregulation of Gene Expression Following Human Lung Transplantation
Background: Lung transplantation remains the only viable treatment option for the majority of patients with advanced lung diseases. However, 5-year post-transplant survival rates remain low primarily secondary to chronic ...
MicroRNAs in pulmonary arterial hypertension
(American Thoracic Society, 2015)
Pulmonary arterial hypertension (PAH) is a devastating disease without effective treatment. Despite decades of research and development of novel treatments, PAH remains a fatal disease, suggesting an urgent need for better ...
Bioinformatic resources of microRNA sequences, gene targets, and genetic variation
(Frontiers Research Foundation, 2012)
Variation in quantitative gene expression has been observed in natural populations and associated with various complex traits/phenotypes such as risks for common diseases and drug response. MicroRNAs (miRNAs), a family ...
Integrating microRNAs into a system biology approach to acute lung injury
Acute lung injury (ALI), including the ventilator-induced lung injury (VILI) and the more severe acute respiratory distress syndrome (ARDS), are common and complex inflammatory lung diseases potentially affected by various ...