Now showing items 1-3 of 3
Expression profiling of genes regulated by Fra-1/AP-1 transcription factor during bleomycin-induced pulmonary fibrosis
(BioMed Central, 2013-06-07)
Background: The Fra-1/AP-1 transcription factor regulates the expression of genes controlling various processes including migration, invasion, and survival as well as extracellular remodeling. We recently demonstrated ...
MicroRNAs Implicated in Dysregulation of Gene Expression Following Human Lung Transplantation
Background: Lung transplantation remains the only viable treatment option for the majority of patients with advanced lung diseases. However, 5-year post-transplant survival rates remain low primarily secondary to chronic ...
Pharmacogenomic Discovery Delineating the Genetic Basis of Drug Response
(Springer Verlag, 2013-09)
Personalized medicine has the promise to tailor medical care based on the patient’s genetic make-up and clinical variables such as gender, race and exposure to environmental stimuli. Recent progress in pharmacogenetic and ...