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cAMP-dependent protein kinase is essential for hypoxia-mediated epithelial-mesenchymal transition, migration, and invasion in lung cancer cells

Shaikh, Dooniya; Zhou, Qiyuan; Chen, Tianji; Ibe, Joyce Christina F.; Zhou, Guofei; Raj, J. Usha (Elsevier, 2012-12)

Lung cancer is the leading cause of cancer-related death worldwide. Hypoxia is known to increase cancer cell migration and invasion. We have previously reported that hypoxia induces epithelial-mesenchymal transition (EMT) ...