Now showing items 1-2 of 2
Pharmacogenomics of chemotherapeutic susceptibility and toxicity
(BioMed Central, 2012-11)
ABSTRACT: The goal of personalized medicine is to tailor a patient's treatment strategy on the basis of his or her unique genetic make-up. The field of oncology is beginning to incorporate many of the strategies of ...
Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing
(Elsevier Inc., 2014-01)
In congenital Chuvash polycythemia (CP), VHLR200W homozygosity leads to elevated hypoxia inducible factor (HIF) levels at normoxia. CP is often treated by phlebotomy resulting in iron deficiency, permitting us to examine ...