Now showing items 1-2 of 2
A multicolor panel of TALE-KRAB based transcriptional repressor vectors enabling knockdown of multiple gene targets
(Nature Publishing Group, 2014-12-05)
Stable and efficient knockdown of multiple gene targets is highly desirable for dissection of molecular pathways. Because it allows sequence-specific DNA binding, transcription activator-like effector (TALE) offers a new ...
Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing
(Elsevier Inc., 2014-01)
In congenital Chuvash polycythemia (CP), VHLR200W homozygosity leads to elevated hypoxia inducible factor (HIF) levels at normoxia. CP is often treated by phlebotomy resulting in iron deficiency, permitting us to examine ...