Now showing items 1-6 of 6
Association of Apolipoprotein E Genotype with Duration of Time to Achieve a Stable Warfarin Dose in African-American Patients
(IOS Press, 2011-08)
Study Objective. To test the hypothesis that genotypes for proteins affecting vitamin K availability influence the duration of time required to achieve a stable warfarin dose in African-American patients. Design. ...
Dosing and monitoring of low-molecular-weight heparin in high-risk pregnancy: Single-center experience
(IOS Press, 2011-07)
Study Objective. To evaluate dosing requirements and monitoring patterns of low-molecular-weight heparin (LMWH) when used in high-risk pregnancy. Design. Retrospective, observational, cohort study. Setting. ...
Pharmacogenomics: application to the management of cardiovascular disease
(Nature Publishing Group, 2011-09)
There have been substantial advances in cardiovascular pharmacogenomics in the past decade. Genetic determinants of response to clopidogrel and warfarin have been defined, resulting in changes to the product label for ...
Carnosol: A Promising Anti-Cancer and Anti-Inflammatory Agent
The Mediterranean diet and more specifically certain meats, fruits, vegetables, and olive oil found in certain parts of the Mediterranean region have been associated with a decreased cardiovascular and diabetes risk. More ...
The Role of Pharmacogenomics in the Management of Traditional and Novel Oral Anticoagulants
(IOS Press, 2011-12)
Warfarin is the most commonly prescribed oral anticoagulant. However, it remains a difficult drug to manage mostly because of its narrow therapeutic index and wide inter-patient variability in anticoagulant effects. Over ...
Glutamatergic gene expression is specifically reduced in thalamocortical projecting relay neurons in schizophrenia
Background—Impairment of glutamate neurons which relay sensory and cognitive information from the medial dorsal thalamus to the dorsolateral prefrontal cortex and other cortical regions may contribute to the pathophysiology ...