Now showing items 1-6 of 6
Training Future Health Providers to Care for the Underserved: A Pilot Interprofessional Experience
(Medknow Publications, 2012-09)
Introduction: Interprofessional teamwork is essential for effective delivery of health care to all patients, particularly the vulnerable and underserved. This brief communication describes a pilot interprofessional learning ...
Cost is not a barrier to implementing clopidogrel pharmacogenetics
(IOS Press, 2012-04)
Tailoring Drug Therapy Based on Genotype
(SAGE Publications, 2012-08)
Polymorphisms in genes encoding drug metabolizing enzymes, drug transporters, and drug targets can influence drug effects and contribute to inter-individual differences in drug response. Genotype for drug metabolizing ...
Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans
(Lippincott, Williams & Wilkins, 2012-02)
Objective Little is known about genetic contributors to higher than usual warfarin dose requirements, particularly for African Americans. This study tested the hypothesis that the γ-glutamyl carboxylase (GGCX) genotype ...
Decreased Warfarin Clearance with the CYP2C9 R150H (*8) Polymorphism
(Nature Publishing Group, 2012-04)
The cytochrome P450 (CYP) 2C9 R150H (*8) allele occurs commonly in African Americans and is associated with lower warfarin dose requirements. We examined whether the CYP2C9*8 allele impacts warfarin clearance through a ...
Influence of Body Weight, Ethnicity, Oral Contraceptives and Pregnancy on the Pharmacokinetics of Azithromycin in Women of Child-Bearing Age
(American Society for Microbiology, 2012-02)
Women of child-bearing age commonly receive azithromycin for treatment of community acquired infections, including during pregnancy. This study determined azithromycin pharmacokinetics (PKs) in pregnant and nonpregnant ...