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dc.contributor.authorVillaflores, Oliver B.
dc.contributor.authorMacabeo, Allan Patrick G.
dc.contributor.authorGehle, Dietmar
dc.contributor.authorKrohn, Karsten
dc.contributor.authorFranzblau, Scott G.
dc.contributor.authorAguinaldo, Alicia M.
dc.date.accessioned2011-05-12T01:43:33Z
dc.date.available2011-05-12T01:43:33Z
dc.date.issued2010-10-20
dc.identifier.bibliographicCitationVillaflores, O. B., Macabeo, A. P. G., Gehle, D., Krohn, K., Franzblau, S. G., & Aguinaldo, A. M. 2010. Phytoconstituents from Alpinia purpurata and their in vitro inhibitory activity against Mycobacterium tuberculosis. Pharmacognosy Magazine, 6(24): 339-344. DOI: 10.4103/0973-1296.71785.en
dc.identifier.issn0973-1296
dc.identifier.otherDOI: 10.4103/0973-1296.71785
dc.identifier.urihttp://hdl.handle.net/10027/7616
dc.descriptionThe original source for this publication is at Medknow Publications. DOI: 10.4103/0973-1296.71785en
dc.description.abstractAlpinia purpurata or red ginger was studied for its phytochemical constituents as part of our growing interest on Philippine Zingiberaceae plants that may exhibit antimycobacterial activity. The hexane and dichloromethane subextracts of the leaves were fractionated and purified using silica gel chromatography to afford a mixture of C-28-C-32 fatty alcohols, a 3-methoxyflavone and two steroidal glycosides. The two latter metabolites were spectroscopically identified as kumatakenin (1), sitosteryl-3-O-6-palmitoyl-beta-D-glucoside (2) and beta-sitosteryl galactoside (3) using ultraviolet (UV), infrared (IR), electron impact mass spectrometer (EIMS) and nuclear magnetic resonance (NMR) experiments, and by comparison with literature data. This study demonstrates for the first time the isolation of these constituents from A. purpurata. In addition to the purported anti-inflammatory activity, its phytomedicinal potential to treat tuberculosis is also described.en
dc.description.sponsorshipThis study was supported by the Philippine Council for Advanced Science and Technology Research and Development, Department of Science and Technology, Manila, and by the Department of Chemistry, College of Science, University of Santo Tomas, Manila.en
dc.language.isoen_USen
dc.publisherMedknow Publicationsen
dc.subjecttuberculosisen
dc.subjectpurpurataen
dc.titlePhytoconstituents from Alpinia purpurata and their in vitro inhibitory activity against Mycobacterium tuberculosisen
dc.typeArticleen


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