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RBM25/LUC7L3 function in Cardiac Sodium Channel Splicing Regulation of Human Heart Failure
Alternative splicing is a post-transcriptional mechanism that can substantially change the pattern of gene expression. Up to 95% of human genes have multi-exon alternative spliced forms, suggesting that alternative splicing ...
Metabolic Stress, Reactive Oxygen Species, and Arrhythmia
Cardiac arrhythmias can cause sudden cardiac death (SCD) and add to the current heart failure (HF) health crisis. Nevertheless, the pathological processes underlying arrhythmias are unclear. Arrhythmic conditions are ...