Pediatric Brain Research and Intervention Center
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Time Course of Recovery Showing Initial Prefrontal Cortex Changes at 16 weeks, Extending to Subcortical Changes by Three years in Pediatric Bipolar Disorder (Elsevier, 2013-09)Objective: Activation changes at the interface of affective and cognitive systems are examined over a three year period in pediatric bipolar disorder (PBD). Methods: Thirteen participants with PBD and 10 healthy controls ...
Fronto-limbic Dysfunction in Mania Pre-Treatment and Persistent Amygdala Over-activity Post-Treatment in Pediatric Bipolar Disorder (Springer Verlag, 2011-03-10)Rationale. Neural deficits at the interface of affect and cognition may improve with pharmacotherapy in pediatric bipolar disorder (PBD). Objectives. We examined lamotrigine treatment impact on the neural interface of ...