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    Torroidal Tunnels

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    SharmaChemicalEngineering.jpg (1.243Mb)
    Date
    2011
    Author
    Sharma, Vishal
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    Abstract
    This image represents a self-assembling tool for the sustained delivery of therapeutic agents. To form this particle, a drop of polymer solution is simply allowed to fall from the tip of a needle into a solution of similar viscosity. While the drop descends, it begins to turn in on itself to form inner channels made up of the outside solution. The end result is a doughnut like shape with spiral tunnels leading inside. This image was taken by a high speed camera that is capable of taking one million images per second. We are able to “freeze” the particle instantly using ultraviolet light so it becomes hard. The goal of this work is to deliver therapeutic agents, such as small drug molecules or proteins using this naturally occurring phenomenon. We can tailor our particle to contain multiple therapeutic agents by dissolving one into the polymer drop and one into the outside solution, which will go into the tunnels all by itself. It’s as if the particle has a mind all its own, leaving onlookers curious to see the limitless possibilities in which it can be used.
    Type
    Image
    Date available in INDIGO
    2012-01-05T19:19:29Z
    URI
    http://hdl.handle.net/10027/8109
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