Configuration of membrane-bound proteins by x-ray reflectivity
Schlossman, Mark L.
PublisherAmerican Institute of Physics
MetadataShow full item record
In this presentation we review our recent work using x-ray reflectivity to determine the configuration of membrane-bound proteins. The reflectivity data is analyzed in terms of the known crystallographic structure of proteins and a slab model representing the lipid layer to yield an electron density profile of the lipid/protein system. Our recent modified analysis methodology for the lipid/protein system is concisely described in this report. In addition, some results of the configuration of the membrane-bound proteins cPLA2a-C2, p40phox-PX, and PKCa-C2 are highlighted.