Browsing Publications - Medicinal Chemistry and Pharmacognosy by Subject "AD mouse models"

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A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease.

Luo, J; Lee, SH; VandeVrede, L; Qin, Z; Ben Aissa, M; Larson, J; Teich, AF; Arancio, O; D'Souza, Y; Elharram, A; Koster, K; Tai, LM; LaDu, MJ; Bennett, BM; Thatcher, GR (BioMed Central, 2016-04-29)

BACKGROUND: Clinical failures singularly targeting amyloid-β pathology indicate a critical need for alternative Alzheimer's disease (AD) therapeutic strategies. The mixed pathology reported in a large population of AD ...