Now showing items 1-5 of 5

    • Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation 

      Wang, Ting; Wang, Lichun; Moreno-Vinasco, Liliana; Lang, Gabriel D.; Siegler, Jessica H.; Mathew, Biji; Usatyuk, Peter V.; Samet, Jonathan M.; Geyh, Alison S.; Breysse, Patrick N.; Natarajan, Viswanathan; Garcia, Joe G. N. (BioMed Central, 2012-08)
      BACKGROUND: Exposure to particulate matter (PM) is a significant risk factor for increased cardiopulmonary morbidity and mortality. The mechanism of PM-mediated pathophysiology remains unknown. However, PM is proinflammatory ...
    • Statins as a novel therapeutic strategy in acute lung injury 

      Singla, Sunit; Jacobson, Jeffrey R. (Medknow Publications, 2012-10)
      Acute lung injury (ALI) is a devastating clinical condition associated with pulmonary and systemic inflammation and characterized by incompetence of the pulmonary microvascular barrier culminating in noncardiogenic pulmonary ...
    • Statins as a novel therapeutic strategy in acute lung injury 

      Singla, Sunit; Jacobson, Jeffrey R. (Medknow Publications, 2012-10)
      Acute lung injury (ALI) is a devastating clinical condition associated with pulmonary and systemic inflammation and characterized by incompetence of the pulmonary microvascular barrier culminating in noncardiogenic pulmonary ...
    • Optimization of isolated perfused/ventilated mouse lung to study hypoxic pulmonary vasoconstriction 

      Yoo, Hae Young; Zeifman, Amy; Ko, Eun A.; Smith, Kimberly A.; Chen, Jiwang; Machado, Roberto F.; Zhao, You-Yang; Minshall, Richard D.; Yuan, Jason X.-J. (Medknow Publications, 2013-04)
      Hypoxic pulmonary vasoconstriction (HPV) is a compensatory physiological mechanism in the lung that optimizes the matching of ventilation to perfusion and thereby maximizes gas exchange. Historically, HPV has been primarily ...
    • Epidemiological and risk analysis of the H7N9 subtype influenza outbreak in China at its early stage 

      Zhuang, QingYe; Wang, SuChun; Wu, MeiLi; Lui, Shuo; Jiang, WenMing; Hou, GuangYu; Li, JinPing; Wang, KaiCheng; Chen, JiMing; Chen, JiWang (SpringerOpen, 2013-09)
      Dozens of human cases infected with H7N9 subtype avian influenza virus (AIV) have been confirmed in China since March, 2013. Distribution data of sexes, ages, professions and regions of the cases were analyzed in this ...